16S & 16S/18S Low Biomass

What will you discover when you get accurate, long-read sequencing from only picograms of input DNA?


Loop Genomics is proud to be the first company to bring you low biomass 16S and 16S/18S microbial metagenomics kits. Specifically designed for studying microbial communities where populations are low, such as in samples obtained from skin, water, air, and hard surfaces, these kits provide all the benefits of LoopSeq technology from only 2-200 picograms of starting DNA.

Through long-reads, de novo molecule assembly, and consensus error correction, we've seen these kits deliver species level results from the hundreds of low biomass samples we've already processed in our service lab.

Sample skin


Find out what microbes are present in healthy skin and see how they're perturbed in disease states with kits designed to maximize microbial DNA while avoiding human DNA. 

Survey hard surfaces


Assesses and monitor pathogens that are living on hard surfaces in areas of concern such as hospitals, food preparation surfaces, and more. Our low biomass technology is already being used to study microbial communities on hospital surfaces in an effort from the Arkansas Children's Hospital Research Institute.

Analyze air


Airborne microbes are another cause for concern, but their low density can make metagenomics studies challenging. Both 16S and 16S/18S Low Biomass Kits are up for the task and are already in use in preliminary studies.

Test water


Whether you're monitoring water quality, looking at the environmental effects of runoff on marine life, or more, microbial communities can provide much-need data for scientific discovery and critical decision-making. 


Multiplex workflow

Pool all samples into a single tube in the first step.


Read V1-V9.

Species classification

Higher resolution microbiome classification.

Better quantification

Barcode based quantification to deliver single molecule sequencing data.

Easy to use

Get the kit

Next day shipping for the sample prep kit.

Upload results

Securely upload FASTQ results to the Loop's cloud pipeline.

Receive data

We've been featured

The exciting thing about [the tech] is that all you need to get started is a sample prep kit.

...better quantify low abundance species than standard Illumina sequencing.

Outsource your sequencing

Process your samples in Loop's lab. Learn more about the service options.

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Loop Genomics
5941 Optical Court
San Jose, CA 95138 USA
Tel: 650-815-7088
Toll-Free: 844-238-1849
Fax: 650-285-2387